3 There have been many calls to develop programmes for adolescents to reduce risk of mental ill-health and promote well-being. Furthermore, broader social, emotional and behavioural problems often appear in this same developmental window, and predict mental health outcomes into adulthood. 2 Preadult onset is associated with poorer lifetime mental health outcomes, greater impairments in social, emotional and occupational functioning, and reduced quality of life. 1 Of all mental health disorders that emerge during adolescence, depression has the largest impact on health throughout the life span in terms of years lost to disability. Mental health problems commonly have their first onset in adolescence. Professor Willem Kuyken, Department of Psychiatry, University of Oxford, Oxford OX3 7JX, UK .ac.uk

10 Department of Psychiatry, University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK.

9 Department of Human Development and Family Studies, The Pennsylvania State University, University Park, Pennsylvania, USA.

8 UCL Institute of Cognitive Neuroscience, London, UK.

7 Department of Psychology, University of Cambridge, Cambridge, UK.

6 Medical Research Council Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.

5 Population, Policy & Practice research programme, UCL Great Ormond St.4 Teaching, Research and Innovation Unit, Parc Sanitari Sant Joan de DГ©u, Sant Boi de Llobregat, Spain.3 KingвЂ™s College London, KingвЂ™s Health Economics, Institute of Psychiatry, Psychology and Neuroscience, De Crespigny Park, London, UK.2 NIHR Applied Research Collaboration South West Peninsula (PenARC), University of Exeter, Exeter, Devon, UK.1 Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.

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